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Psychotherapy

Myrna Weissman, Ph.D.

How should family members be involved in psychotherapy?
We encourage family involvement and meeting with families, but only with patients' approval. We have done studies involving martial partners. We found that often the marital partner was also depressed. For adolescents, we always have the parent involved in the initial phase and may bring in the parent later.

What research are you conducting on depression in families?
We are studying three generations of depression in families. We have grandparents, parents, and children that we have followed for over 15 years. We also have studied depressed children, now grown up, that we followed into adulthood to study the likelihood that childhood depression leads to adult depression.

We are currently looking for siblings for our Genetics of Major Depression Study, the largest study involving at least two siblings that have major depression. This is a study of depression that starts before the age of 30, which is considered to be the most severe with the most familialty. We compare the genetic material of siblings (blood samples) to help us discover the gene location for major depression.

What results have you found about families from your studies?
We have confirmed that depression runs in families. It is not inevitable and you are not doomed if you have depression in your family, but your risk is increased. If the general population risk for depression is 10%, your risk may be 30%. Also, depression runs in generations, so grandchildren can develop depression. Usually the first signs are not depression, but anxiety disorders, which occur before puberty.

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© 2001 Families for Depression Awareness

Psychotherapy
Dr. Myrna Weissman is the director of the Clinical and Genetic Epidemiology at the NY State Psychiatric Institute

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